Games. Our findings provide further evidence of an adverse association between disinfectants and cleaning products and respiratory health. SC, Benke Nonetheless, the latter differences by smoking or asthma status were not statistically significant (all P for interaction > .15). On the left screen, blue blocks will appear shining, and the player must memorize the correct sequence and then select the buttons that make up the sequence, but if he misses, the player must start all over again. Analyses were conducted using SAS, version 9.4 (SAS Institute Inc). et al. Su JAMA Netw Open. A few European studies have reported an increased risk of COPD,16,17 accelerated lung function decline,9 and higher rates of death due to COPD18 among cleaning workers. B, Johanson Customize your JAMA Network experience by selecting one or more topics from the list below. This task is possibly the best for impostors to pretend making because of the time it takes for a crewmate to do. In a cohort study of 73 262 US female nurses participating in the Nurses’ Health Study II who were followed up from 2009 to 2015, occupational exposure to cleaning products and disinfectants was significantly associated with a 25% to 38% increased risk of developing chronic obstructive pulmonary disease independent of asthma and smoking.
When the player opens the task, a screen with a keyboard will appear. Occupations associated with COPD risk in the large population-based UK Biobank cohort study. R, Zerimech Fourth, despite the prospective design and exclusion of all women with COPD before baseline, we cannot exclude the possibility that our results may be subject to a healthy worker effect. M, Jégu FE. N, Markkanen M, Boutron-Ruault
To evaluate specific exposures in large cohorts, the use of job-exposure matrices is generally favored over self-report.39 In this population of nurses, we further showed that using a JTEM, which assigns exposure level based not only on nursing job types but also on disinfection tasks, provides better exposure estimates than a job-exposure matrix by reducing exposure misclassification.14,24 Nursing job types and disinfection tasks were self-reported; however because associations were evaluated prospectively (ie, exposure was evaluated before the report of COPD diagnosis), differential recall bias is unlikely. However, we may have underestimated the association between disinfectant exposures and COPD development, because the reference group (nurses currently nonexposed) likely includes women who had been exposed in the past. Clean and complete data used for this analysis were available in July 2018, and analyses were conducted from September 2018 through August 2019. Mansournia Ø, Skorge © 2019 Dumas O et al.
Indeed, women with respiratory conditions or symptoms that sometimes precede COPD development, such as asthma, may have left exposed jobs before a COPD diagnosis.
PK, Braun L, Sjögren
In each model, occupational exposure was handled as a time-varying variable and was evaluated as the highest exposure level at any of the questionnaire cycles before time of diagnosis. Despite this potential bias, significant associations between disinfectant exposures and COPD incidence were found among women both with and without a history of asthma. doi:10.1001/jamanetworkopen.2019.13563. GBD 2016 Disease and Injury Incidence and Prevalence Collaborators. Cummings The NHSII was initially designed to study women’s health (eg, long-term health effects or oral contraceptive use; determinants of major chronic diseases in women, such as breast cancer or cardiovascular disease), and the range of risk factors and health outcome data collected has expanded over time.22 Information on occupational exposures was collected for the first time in 2009, which was defined as the baseline for the present study. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 report: GOLD executive summary. M, Virji Dumas Error bars indicate 95% CIs. to download free article PDFs, M-C, Adjusted hazard ratios (AHRs) with 95% CIs are shown for type of disinfectant (A and B) and specific use of disinfectant (C and D).
Varraso Population attributable fraction. et al. To investigate the association between exposure to disinfectants and COPD incidence in a large cohort of US female nurses. This study’s findings suggest that regular use of chemical disinfectants among nurses may be a risk factor for developing chronic obstructive pulmonary disease. KJ, Johnson Then, because nurses were often classified as exposed to multiple products, we studied exposure to combinations of several specific products evaluated by the JTEM14 for the products found associated with COPD when studied separately. Is exposure to disinfectants and cleaning products associated with incidence of chronic obstructive pulmonary disease among health care workers? When we examined the types of disinfection tasks, the association between use of disinfectants to clean surfaces only and COPD incidence was more pronounced among ever smokers and participants without asthma, whereas the association between use of disinfectants to clean medical instruments and COPD incidence was more pronounced among never smokers and participants with asthma.
EB, WC, Speizer et al.
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