Because of its long read lengths and flexible run conditions, the Sequel II is adept at de novo genome sequencing in species for which no reference genome is yet available, says Shawn Levy, a geneticist at the nonprofit HudsonAlpha Institute for Biotechnology, which was given early access to the instrument. “[Patients] find the process noninvasive compared to other ways of taking samples, such as taking blood samples or tissue biopsies,” adds Irene Debiram-Beecham, a principal research nurse at the University of Cambridge who helped coordinate recent studies in Fitzgerald’s lab. 10X’s droplet-based approach scaled the throughput of single-cell ATAC sequencing from a few hundred that could be done manually to thousands or tens of thousands of cells per run, says Fergus Chan, cofounder of Epinomics and now director of product management at 10X. “That’s the beauty of a device like this. Outperforming existing computer vision SLAM systems (simultaneous localization and mapping), a new technology developed by researchers at the University of Essex utilises deep learning neural networks to facilitate real-time localisation and simultaneous environment mapping, with the potential to disrupt robotics, healthcare and autonomous vehicles. Patients can check their glucose by swiping a smartphone loaded with the FreeStyle LibreLink app across the sensor, or they can buy the FreeStyle Libre reader for a one-time cost of $70. Kamdar began her career as a scientist and pursued drug-discovery research at Novartis/Syngenta for nine years. “The big advantage is that you know what you’re looking for,” says Billy Boyle, cofounder and CEO of Owlstone Medical. In the air, the straw appears normal, but in the lemonade, it appears bent, or refracted. His aim with CODEX is to “get the most data from small samples of tissues to understand as much of the tumor micro-environment as possible.”, Wiley: “Although multiplexed antibody detection systems have been described before, the simplicity .
This is a sort of quantum leap from what people were doing.”, Cruickshank-Quinn: “Being able to visualize phenotypes and perform functional assays on thousands of individual cells simultan-eously allows users to obtain results in a fraction of the time. . Senior Research Scientist and Laboratory Fellow at Pacific Northwest National Laboratory. With a swipe of a cellphone across a sensor attached to the back of his arm, Michael Krauser can instantaneously check his glucose levels. In short order, the University of Oxford spun out Refeyn to commercialize mass photometry, and its Refeyn OneMP instruments went on the market in March of 2019, starting at roughly $150,000. The alerts are extremely helpful to children and other patients who might not other-wise know of extreme changes in their glucose levels, especially during sleep, says Marc Taub, the divisional vice president of product development for diabetes care at Abbott. Janus bases also have two binding faces, allowing them to slip between the two sides of double-stranded nucleic acids, and bind to both of the complementary strands with stronger affinity than the two natural strands have to each other.
Abbott’s FreeStyle Libre 2 is an “elegant” solution to checking his glucose that “adds a certain security to my life,” he says. With a view to providing the consumer goods industry with viable options for natural ingredients, scientists at North Carolina State University have laid the foundation for a new green cleaning product that combines the antimicrobial properties of green tea with copper ions as an effective, safe, and fast-acting natural disinfectant. The company is now beginning mouse experiments, says Dietrich Stephan, cofounder, chairman, and CEO of NeuBase, with clinical trials projected to begin in 2021. Definitely could greatly accelerate research in understanding gene function in cells.”. Edited by Alex Stockham. Cruickshank-Quinn was a research fellow at National Jewish Health in Denver before becoming a postdoc and then instructor at the University of Colorado Anschutz Medical Campus. The company won a spot in last year’s Top 10 with an mRNA that codes for the DNA-cutting nuclease Cas9, while this year’s winning invention combines the sequences for Cas9 and the single guide RNA (sgRNA) that leads the enzyme to the appropriate spot in the genome, all packaged into a viral vector. Box 3118 Indian Trail, NC 28079 Tel: 888-505-2988 Fax: 704-821-3413 A new technology from researchers at the Max Planck Society has unlocked the possibility of creating magnetically-programmable active surfaces that can change shape in seconds with high spatial and temporal resolution for future applications in robotics, engineering, material science and medicine. The instrument’s capacity to collect data on multiple markers per sample was a selling point for Andras Heczey, an oncology researcher at Baylor College of Medicine who has used CODEX for antibody validation and plans to deploy it to analyze how immunotherapy treatments interact with cancers. .
“The platform is in the ballpark of a very high-end microscope,” he says.
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